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| 5 June | 6 June | 7 June | 8 June | 9 June | 10 June |
please
note that Presentations for which the
powerpoint presentation is available has been linked
in this color
SUNDAY
5 June, 2011 - Pre-meeting symposium
| Time | Topic |
Speaker |
| Pre-meeting Symposium: The Diagnostic and Therapeutic Challenges of the Sensitized Patient |
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| Session: PRE-TRANSPLANT : The patients, the tools, the protocol | Chairs: Denis Glotz and Paul Terasaki | |
| 8:00 - 8:30 | Introduction and definition of the problems of sensitized patient | Denis Glotz |
| 8:30 - 8:55 | Defining the risk pre-transplant | Carmen Lefaucheur |
| 8:55 - 9:20 | Luminex technology : value and limitations | Howard Gebel |
| 9:20 - 9:45 | IgG sub-classes of anti-HLA Abs | Paul Terasaki |
| 9:45 - 10:10 | Complement Fixing Antibodies | Adriana Zeevi |
| 10:10 - 10:35 | Flow crossmatch : value and limitations | Andrea Zachary |
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| 10:35 - 11:00 | Coffee Break | |
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| 11:00 - 11:30 | Cadaveric transplant desensitization protocols | Stanley C. Jordan |
| 11:30 - 12:00 | Living Donor transplant desensitization protocols | Bob Montgomery |
| 12:00 - 12:30 | Eculizumab: a new concept ? | Mark Stegall and James Gloor |
| 12:30 - 1:15 | Round table: standardization/ common protocols | Open to all participants |
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| 1:15 - 2:15 | Lunch | |
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| Session: POST-TRANSPLANT : Long term outcomes and therapeutic goal | Chairs: James Gloor and Arthur Matas | |
| 2:15 - 2:45 | Defining the challenges long term | Robert Colvin |
| 2:45 - 3:15 | Findings from protocol biopsies | Alexandre Loupy |
| 3:15 - 3:45 | Antibodies post : the DEKAF study | Michael Cecka |
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| 3:45 – 4:15 | Coffee Break | |
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| 4:15 – 4:45 | Defining relevant endpoints | Phil Halloran |
| 4:45 – 5:15 | The potential of IVIg/Ritux | Stanley C. Jordan |
| 5:15 – 5:45 | The potential of Bortezomib | Steven Woodle |
| 5:45 – 6:15 | The potential of others drugs | James Gloor |
| 6:15 – 6:45 | Round table : shaping up therapeutic interventions | Open to all participants |
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| Free Evening | ||
MONDAY 6 June, 2011 - day one: Banff conference
| Time | Topic |
Speaker |
| 2:00 - 4:00 | REGISTRATION | |
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| 4:00 - 4:30 | Opening and Welcome | Kim Solez, Lorraine Racusen |
| 4:30 - 5:00 | Structure and Governance of Banff Meetings | Kim Solez |
| 5:00 - 5:30 | Report from the pre-meeting on antibody-mediated rejection | Denis Glotz |
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| 6:30 | Welcome Reception - Cocktails and Snacks. Open bar |
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TUESDAY 7 June, 2011 - Day two: Banff conference
| Time | Topic |
Speaker |
| Plenary Session: Progress Report Banff Working groups | Chairs: Michael Mengel and Robert Colvin | |
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| 8:00 - 8:30 | Introduction and progress report on the C4d and BK BIFQUIT trial | Michael Mengel and Parmjeet Randhawa |
| 8:30 - 9:00 | Progress report of the glomerular lesions working group | Banu Sis and Mark Haas |
| 9:00 - 9:30 | Progress report of the isolated v-lesions working group | Banu Sis |
| 9:30 - 10:00 | Progress report on the implantation biopsy working group | Helen Liapis |
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| 10:00 - 10:30 | Coffee Break | |
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| 10:30 - 11:00 | Progress report of the Polyoma classification working group | Volker Nickeleit |
| 11:00 - 11:30 | Computerized quantification of interstitial fibrosis | Eric Thervet |
| 11:30 - 12:00 | Progress report of the fibrosis working group | Robert Colvin |
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| 12:00- 1:00 | Working Lunch: Discussion of Working group findings and potential implementation of new working groups | Chair: Michael Mengel |
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| To view concurrent sessions separately, click on the link. | Concurrent Session - Kidney: Microvascular and arterial lesions in the sensitized patient | Chairs: Denis Glotz and Georg Boehmig |
| Concurrent Session - Liver | Chair: Jake Demetris and Stefan Hübscher | |
| Concurrent Session - Lung | Chair: Carol Farver and W. Dean Wallace | |
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| 1:00 - 1:30 | Kidney: Significance of microcirculation lesions in sensitized patients and the influence of treatment | Lynn Cornell |
| 1:00 - 1:40 | Liver: Introduction and discussion of a need to integrate multiple modalities for biopsy analysis for optimizing outcome | Jake Demetris |
| 1:00 - 1:30 | Lung: Immunology of AMR in lung transplant | Medhat Askar |
| 1:30 - 2:00 | Kidney: Significance of scoring glomerultiis | Parmjeet Randhawa |
| 1:30 - 2:05 | Liver: Histopathology of long-surviving adult liver allograft recipients from a Protocol Biopsy Center | Mylene Sebagh |
| 1:30 - 2:00 | Lung: Pathology of AMR in lung transplants | W. Dean Wallace |
| 2:00 - 2:30 | Kidney: The significance and pathogenesis of transplant glomerulopathy - an update | James Gloor |
| 2:05 - 2:40 | Liver: Special considerations in pediatric recipients - similar findings, but conflicting explanations from different centers | Stefan Hübscher |
| 2:00 - 2:30 | Lung: Clinical features of AMR in lung transplants | Ramsey Hachem |
| 2:30 - 3:00 | Kidney: Antibody independent pathways for development of transplant glomerulopathy | Enver Akalin |
| 2:40 - 3:15 | Liver: Can mRNA expression array analysis associated with recurrent HCV and other causes of late liver allograft dysfunction improve patient classification and morphologic analysis of biopsies | Banu Sis |
| 2:30 - 3:00 | Lung: Non-BOS graft dysfunction | Martin Iversen |
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| 3:00 - 3:30 | Lung and Kidney: Coffee Break |
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| 3:30 - 4:00 | Kidney: Antibody-mediated intimal arteritis | Carmen Lefaucheur |
| 3:15 - 3:50 | Liver: Clinical perspective on the use of biopsy findings in immunosuppression management in conjunction with recent monitoring studies | Graeme Alexander |
| 4:00 - 4:20 | Liver: Coffee Break | |
| 3:30 - 4:00 | Lung: Panel discussion on diagnosis of AMR in lung transplant | Carol Farver |
| 4:00 - 4:30 | Kidney: Immuno-phenotyping of intimal arteritis | Anthony Chang |
| 4:20 - 4:55 | Liver: Weaning of immunosuppression in adult and pediatric liver allograft recipients – Where are we, what do we know, and where should we go? | Sandy Feng |
| 4:00 - 4:30 | Lung: Infections in lung transplant | Susan Stewart |
| 4:30 - 5:00 | Kidney: Antibody-mediated arteriosclerosis | Gary Hill |
| 4:55 - 5:30 | Liver: Histpathological, immunological, and clinical aspects of immunosuppression free patients after pediatric living-donor liver transplantation - Update of Kyoto experience | Takaaki Koshiba |
| 4:30 - 5:00 | Lung: Endothelial cells in Lung Allograft | John Belperio |
| 5:00 - 5:30 | Kidney: The value of electron microscopy in early biopsies from high-risk antibody patients | Brian Nankivell |
| 5:35 - 6:05 | Liver: Can Liver Biopsy mRNA Expression Arrays Provide Insights into Intra-graft events associated with long term dysfunction and ability to wean immunosuppression? | Alberto Sanchez-Fueyo |
| 5:30 - 6:00 | Kidney: Following incompatible renal allografts | Edward Kraus |
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| 6:30 | Case presentations |
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WEDNESDAY 8 JUNE, 2011 - Day three: Banff conference
| Time | Topic |
Speaker |
| Concurrent Morning Session: Plenary Session: Role of parenchyma in allograft deterioration | Chairs: Lorraine Racusen, Roslyn Mannon | |
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| 8:00 - 8:20 | EMT, does it exist? - a critical up-date - No. | Hermann-Josef Gröne |
| 8:20 - 8:40 | EMT, does it exist? a critical up-date - Yes. | Alexandre Hertig |
| 8:40 - 9:00 | EMT of bile duct epithelium | John Andrew Kirby |
| 9:00 - 9:20 | EMT in BOS | Andrew Fisher |
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| 9:20 - 10:00 | Coffee Break | |
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| 10:00 - 10:30 | Molecular mechanisms of nephron loss | Gunilla Einecke |
| 10:30 - 11:00 | Molecular correlates of donor-specific antibodies effects in the tissue | Luis Hidalgo |
| 11:00 - 11:30 | The unfolded protein response in epithelial cells | Nicolas Pallet |
| 11:30 - 12:00 | Discussion | Open to all participants |
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| 12:00 - 1:00 | Working Lunch: Should C4d-negative ABMR be integrated into the Banff classification? | Banu Sis, Alexandre Loupy, Mark Haas |
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| To view sessions concurrent separately, click on the link. |
Concurrent Session: Heart |
Chairs: Rene Rodriguez and Marisa Crespo |
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Concurrent Session: Pancreas |
Chairs: Cinthia Drachenberg and Edward Kraus | |
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Concurrent Session: Vascularized Composite Allografts/Allotransplantation (1-4 pm) |
Chairs: Alton B Farris and Linda Cendales | |
| 1:00 - 1:30 | Heart: Towards a new ISHLT antibody mediated rejection criteria | Rene Rodriguez |
| 1:00 - 1:30 | Pancreas: Clinicopathological integration in pancreas transplantation | Ugo Boggi |
| 1:00 - 1:20 | Composite Allografts: Chronic immune injury in solid organ transplantation | Michael Mengel |
| 1:30 - 2:00 | Heart: Are histological lesions needed for diagnosis of cardiac AMR before further injury occurs? | Marny Fedrigo |
| 1:30 - 2:00 | Pancreas: Enteroscopic biopsies of pancreas allografts | Christian Margreiter |
| 1:20 - 1:40 | Composite Allografts: Chronic changes in non-human primates | Gerhard Mundinger |
| 2:00 - 2:30 | Heart: Symptomatic and asymptomatic cardiac antibody mediated rejection | Maryl Johnson |
| 2:00 - 2:30 |
Pancreas:
Pathological aspects of beta cell failure in
pancreas and islet transplantation |
Phillip Ruiz |
| 1:40 - 2:00 | Composite Allografts: Histologic findings in late vascularized composite allotransplantation, | Jean Kanitakis |
| 2:30 - 3:00 | Heart: C4d positive biopsy without dysfunction: accommodation or subclinical rejection? | Carmela D. Tan |
| 2:30 - 3:00 |
Pancreas:
Comparison between paraffin embedded and Immunofluorescence C4d staining |
Erika Rangel |
| 2:00 - 2:20 | Composite Allografts: Chronic findings in vascularized composite allotransplantation: histologic changes in failed VCA | Linda Cendales |
| 2:20 - 4:00 | Composite Allografts: Consensus Discussions | Linda Cendales, All |
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| 3:00 - 3:30 | Pancreas and Heart: Coffee Break | |
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| 3:30 - 4:00 | Heart: Redefining patterns and significance of late rejection in the era of AMR | Jean Paul Duong van Huyen |
| 3:30 - 4:00 |
Pancreas: Comparison of C4d staining
in paraffin embedded sections versus IF staining |
Dae Un Kim |
| 4:00 - 4:30 | Heart: New serologic markers in cardiac AMR: Incidence and diagnostic utility | John Smith |
| 4:00 - 4:30 |
Pancreas:
Stereotypical T-cell mediated rejection versus antibody mediated rejection. Is there any need for upgrading the Banff grading schema? |
John Papadimitriou |
| 4:00 - 4:05 | Digital Pathology Session: Session Introduction | Jake Demetris |
| 4:05 - 4:20 | Digital Pathology Session: New tools for histopathology and molecular data extraction from tissue specimens | Kumiko Isse |
| 4:30 - 5:00 | Heart: Improving diagnostic from EMB by biopsy-based gene expression profiling | Michael Mengel |
| 4:30 - 5:00 |
Pancreas: Reproducibility issues
and the challenge of developing a uniform morphological approach |
Erika Bracamonte |
| 4:20 - 5:00 | Digital Pathology Session: FarSight: A next-generation toolkit of image analysis | Badrinath Roysam |
| 5:00 - 5:30 | Pancreas: Discussion | Open to all participants |
| 5:00 - 6:00 | Digital Pathology Session: Commercial solutions in digital pathology - What is offered? | Representatives of Aperio, Philips, and Omnyx (20 minutes each) |
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| 5:00 - 6:00 | Heart: Discussion | Open to all participants |
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| 6:30 | Poster Presentations | |
| 8:30 | Poetry Session with Drs. Manuel Martinez Maldonado, Kim Solez and Larry Hunsicker (with food) | |
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THURSDAY 9 JUNE, 2011 - Day four: Banff conference
| Time | Topic |
Speaker |
| Plenary Session: Molecular pathology in transplantation | Chairs: Banu Sis and Phil Halloran | |
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| 8:00 - 8:30 | A combined molecular- histopathology Banff classification - addressing unmet needs in diagnostics | Phil Halloran |
| 8:30 - 9:00 | Molecular diagnosis of antibody-mediated rejection | Banu Sis |
| 9:00 - 9:30 | Molecular definition of the stable transplant recipient | Alberto Sanchez-Fueyo |
| 9:30 - 10:00 | Lessons from microRNA studies in kidney transplant biopsies | Dany Anglicheau |
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| 10:00 - 10:30 | Coffee Break | |
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| 10:30 - 11:00 | The molecular phenotype of lung allografts | Adriana Zeevi |
| 11:00 - 11:30 | The molecular phenotype of skin rejection in composite tissue allografts | Theresa Hautz |
| 11:30 - 12:00 | A new integrated diagnostic system - a biostatisticial approach | Jeff Reeve |
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| 12:00 - 1:00 |
Working Lunch: Integrating molecular diagnostics into the Banff classification |
Phil Halloran |
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| To view sessions separately, click on the link. |
Concurrent Session: Liver |
Chairs: Jake Demetris, Stefan Hübscher |
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Concurrent Session: Kidney: Novel insights from protocol biopsies |
Chairs: Mark Haas and Lynn Cornell | |
| 1:00 - 1:40 | Liver: An overview of laboratory testing methods and pathogenesis of antibody-mediated rejection (AMR) with emphasis on liver allografts | Adriana Zeevi |
| 1:00 - 1:30 | Kidney: Ten year protocol biopsy experience in low risk patients | Verena Bröcker |
| 1:40 - 2:20 | Liver: The use of C4d in establishing a diagnosis of AMR in ABO- compatible and incompatible liver allograft recipients | Hironori Haga |
| 1:30 - 2:00 | Kidney: Interplay of subclinical fibrosis and inflammation | Daniel Séron |
| 2:20 - 3:00 | Liver: Use of DSA and C4d Staining in Establishing a Diagnosis or Contribution of AMR to Liver Allograft Injury | Alexandru Musat |
| 2:00 - 2:30 | Kidney: Use of protocol biopsies in multicentre trials | Barbara Murphy |
| 3:00 - 3:40 | Liver: Use of mRNA expression analysis in better understanding the pathogenesis of AMR and what signaling pathways should be looked for? | Banu Sis |
| 2:30 - 3:00 | Kidney: The molecular phenotype of six-week protocol biopsies | Michael Mengel |
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| 3:00 - 3:30 | Kidney: Coffee Break | |
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| 3:40 - 4:00 | Liver: Coffee Break | |
| 3:30 - 4:00 | Kidney: The molecular phenotype of one-year protocol biopsies | Walter Park |
| 4:00 - 6:00 | Liver: Discussion of Consensus Paper | All |
| 4:00 - 4:30 | Kidney: Urine correlates of protocol biopsy findings | David Rush |
| 4:30 - 5:00 | Kidney: Non-invasive biomarker signatures as a new tool for stratifying biopsy indications | Sophie Brouard |
| 5:00 - 5:30 | Kidney: Changes in long-term protocol pathology with modern immunosuppression | Brian Nankivell |
| 7:00 - 11:00 | Gala Dinner | |
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FRIDAY 10 JUNE, 2011 - Day five: Banff conference
| Time | Topic |
Speaker |
| Plenary Session: Summary of organ sessions and future outlook | Chairs: Kim Solez and Lorraine Racusen | |
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| 8:00 - 8:30 | Kidney | Michael Mengel |
| 8:30 - 9:00 | Liver | Jake Demetris |
| 9:00 - 9:30 | Heart | Rene Rodriguez |
| 9:30 - 10:00 | Lung: AMR proposal in lung transplant rejection | Carol Farver and Dean Wallace |
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| 10:00 - 10:30 | Coffee Break | |
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| 10:30 - 11:00 | Pancreas | Cinthia Drachenberg |
| 11:00 - 11:30 | Composite Tissue | Linda Cendales |
| 11:30 - 12:00 | Closing remarks | Kim Solez and Lorraine Racusen |
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| 12:00 - 1:00 | Lunch | |
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